Figure 4: ATAC-peaks corresponding to the area around DMPK.
From: Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability
(A) GenomeJack Browser tracks show ATAC-peaks of control CMs and DM1-CMs (red tracks, control and DM1) as well as CTCF ChIP-seq (green track) and DNase-seq (red track, bottom) of CMs from the database of ENCODE project. Pink bars indicate ATAC peaks of control CMs. + and *indicate differential ATAC peaks between control CMs and DM1-CMs (trimmed mean of M-values (M) >1: tag ratio after normalization >2; +p < 0.01, *p < 10−5). (B) Magnified image of A in the area around DMPK: differential ATAC peaks shown by ** are located between CTCF site 1 and CTCF site 2.
