Figure 1: Effect of 17β-estradiol (E2) treatment on cognitive function after BCCAO 3 months. | Scientific Reports

Figure 1: Effect of 17β-estradiol (E2) treatment on cognitive function after BCCAO 3 months.

From: Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia

Figure 1: Effect of 17β-estradiol (E2) treatment on cognitive function after BCCAO 3 months.

(a) Latency trail in Morris water maze, *P < 0.05 vs. sham (Sh) 3-months (3 m) group at the same time-point; #P < 0.05 vs. Placebo (Pla) group at the same time-point; ^P < 0.05 vs. sham group at day one; $P < 0.05 vs. E2-treatment group at day one; &P < 0.05 vs. Pla group at day one. (b) Probe trail in Morris water maze. *P < 0.05 vs. sham and #P < 0.05 vs. Pla group at the same time-point. Representative tracks for latency trail (c: 1, sham; 2, Pla; 3, E2-treatment) and for probe trail (d: 4, sham; 5, Pla; 6, E2-treatment); n = 6/group.

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