Figure 4: Micrograph of Golgi staining shows apical dendrites from hippocampal CA1 pyramidal neurons. | Scientific Reports

Figure 4: Micrograph of Golgi staining shows apical dendrites from hippocampal CA1 pyramidal neurons.

From: Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia

Figure 4: Micrograph of Golgi staining shows apical dendrites from hippocampal CA1 pyramidal neurons.

(a) The left panel shows whole hippocampus (magnification 10×). The middle panel shows higher magnification of a pyramidal neuron from left panel marked by red arrow (20×). The right panel shows apical dendrites that are magnification of the boxes in the middle panel (100×). Blue arrows indicate mushroom spines. (b) Total number of spine per 20 μm apical dendrites. (c) Mushroom-like spine per 20 μm apical dendrites. (d) Western blot analysis for the spine marker spinophilin, and β-actin. Quantitative analysis for spinophilin shown as mean ± SE (n = 4–5 in each group). Data were expressed as ratio to β-actin. *P < 0.05 vs. sham 3 m control, #P < 0.05 vs. Pla 3 m group.

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