Table 1 Clinical variables and CT perfusion parameters in CMS and non-CMS groups.

From: Cerebral Edema in Chronic Mountain Sickness: a New Finding

Variables

CMS (N = 30)

Non-CMS (N = 15)

P value

Age, years

43.5 ± 7.30

42.3 ± 3.5

0.330

Body-mass index (kg/cm2)

24.3 ± 1.3

24.6 ± 1.6

0.332

Hemoglobin (g/dl)

23.1 ± 1.6

14.6 ± 6.9

<0.001

Hematocrit (%)

70.9 ± 4.2

45.5 ± 5.4

<0.001

HR (beats/min)

83.7 ± 14.1

77.6 ± 13.9

0.221

SpO2 (%)

85.1 ± 4.8

93.1 ± 2.8%

<0.001

Forced Vital Capacity, FVC (l)

4.23 ± 0.67

4.41 ± 0.77

0.136

FEV1/FVC %

87.69 ± 5.43

88.31 ± 5.24

0.491

FEF 25–75% (l/s)

3.30 ± 0.64

3.18 ± 0.59

0.261

CMS score

13 [8–20]

1 [1–2]

<0.0001

CT value of SSS (HU)

55.91 ± 4.61

46.39 ± 2.76

<0.01

CT value of BMCA (HU)

51.29 ± 5.13

38.83 ± 3.29

<0.01

ACA-TDC (s)

25.50 ± 5.20

19.87 ± 2.26

<0.05

SSS-TDC (s)

35.92 ± 5.68

26.80 ± 3.69

<0.001

White Matter

CBF [ml/(100 ml/min)]

15.6 ± 3.4

17.3 ± 3.6

0.270

TTP (s)

17.4 ± 2.6

15.1 ± 3.3

0.121

CBV (ml/100 g)

2.91 ± 1.1

3.07 ± 0.9

0.453

MTT (S)

10.7 ± 2.0

6.69 ± 2.3

0.004

Grey Matter

CBF [ml/(100 ml/min)]

30.4 ± 4.8

40.5 ± 3.9

0.001

TTP (s)

14.0 ± 2.5

11.0 ± 2.3

0.017

CBV (ml/100 g)

4.60 ± 1.0

4.47 ± 0.9

0.358

MTT (s)

6.51 ± 1.6

3.97 ± 0.7

0.004

  1. Data expressed as mean ± standard deviation, FEV1%, percent of forced expiratory volume in 1 second; FEF25–75%, mean forced expiratory flow during half of the forced vital capacity; SSS, superior sagittal sinus; BMCA, bilateral middle cerebral artery; ACA-TDC, anterior cerebral artery time delay curve; SSS-TDC, superior sagittal sinus time delay curve; CBF, cerebral blood flow; TTP, time-to-peak; CBV, cerebral blood volume; MTT, mean transit time.