Figure 3: Characteristics of 7 neurofibroma macrophages.

DEGs from 7-to-1 month comparison of macrophages (a,b) were mapped to M1/M2 polarization signature genes collected from previous publications. Only differentially expressed signature genes were displayed. Macrophage (MΦ) subpopulation clusters were generated by exploratory factor analysis (EFA) approach, based on (c) all genes in the microarray, (d) ligands and receptor genes, and (e) M1/M2 signature genes19.