Figure 2: Resting-state functional connectivity networks.

Representative orthogonal slices showing z(r)-values (thresholded for |z(r)| ≥ 0.4) as functional connectivity heat maps in MNI space for (A) motor and (B) basal ganglia-thalamic networks for far from onset preHD (left columns) and controls (right columns). Hot colors indicate the strength of the correlation as an indirect measure of functional connectivity. The averaged study-specific echo planar imaging (EPI) is used as background. Voxel-wise group comparisons for each network between far from onset preHD and control subjects revealed no significant differences indicating similar functional networks in both groups.