Table 2 Demographics and clinical characteristics.

From: Intact sensory-motor network structure and function in far from onset premanifest Huntington’s disease

 

Far from onset preHD (N = 12)

Healthy controls (N = 22)

p-value

Sex (male:female)

3:9

15:7

0.030a

Age/y

36 (32–46), 27–62

45 (39–49), 25–51

0.287b

UHDRSb total motor score

2 (1–3), 0–9

  

Years of education

14 (12–14), 9–17

17 (14–18), 12–19

0.047b

CAGn repeat size

40 (40–42), 39–44

n/a

n/a

Disease-burden scored

202 (169–222), 102–233

n/a

n/a

Predicted years to onsete

23 (19–29), 14–43

n/a

n/a

Verbal fluency

42 (37–50), 30–54

41 (33–50), 25–52

0.851b

Stroop color

80 (62–91), 35–100

79 (69–88), 48–96

0.808b

Stroop interference

55 (44–64), 18–106

49 (44–54), 34–65

0.359b

Stroop read

97 (78–114), 43–128

100 (92–134), 74–150

0.201b

SDMTf

56 (46–67), 25–79

53 (50–60), 35–85

0.940b

  1. Data are shown as median (interquartile range), min–max. aFisher’s exact test; bMann-Whitney-U-test; cUnified Huntington’s Disease Rating Scale; dDisease burden score [age × (CAGn-35.5)]; eEstimated disease onset at a 60% certainty level according to refs 9 and 40; fSymbol Digit Modalities Test; NA, not applicable.
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