Figure 5: Reduced tissue resistance after C. jejuni infection in gnotobiotic piglets. | Scientific Reports

Figure 5: Reduced tissue resistance after C. jejuni infection in gnotobiotic piglets.

From: Analysis of Campylobacter jejuni infection in the gnotobiotic piglet and genome-wide identification of bacterial factors required for infection

Figure 5: Reduced tissue resistance after C. jejuni infection in gnotobiotic piglets.

Analysis was performed on tissue derived from piglets infected with C. jejuni strain 81–176 (4 days p.i.) and uninfected control animals in an Ussing Chamber model. No difference in potential difference (a) or change in short circuit current (b) across mucosa was observed between infected or uninfected samples, however tissue resistance (c) was significantly reduced in infected animals, indicating a more leaky bowel. Statistical significance was analysed using a two-tailed Mann-Whitney (non-parametric) test with **P < 0.01.

Back to article page