Table 1 Summary the effects of all pharmacological interventions in each cardiac parameter.
Cardiac parameters | ND | HFeV | HFeDFO | HFeDFP | HFeDFX | HFeNAC | HFeDFP + NAC |
|---|---|---|---|---|---|---|---|
Echocardiography | |||||||
- % LVEF | +++ | + | ++ | ++ | ++ | ++ | +++ |
Intracellular Ca 2+ transients | |||||||
- Amplitude | +++ | + | ++ | ++ | ++ | ++ | +++ |
- Rising rate | +++ | + | ++ | ++ | ++ | ++ | +++ |
- Decay rate | +++ | + | +++ | +++ | +++ | +++ | +++ |
- Diastolic Ca2+ level | +++ | ++++ | +++ | +++ | +++ | +++ | +++ |
The levels of Ca 2+ cycling protein | |||||||
- LTCC | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
- TTCC | + | ++ | ++ | ++ | ++ | ++ | ++ |
- SERCA | +++ | + | +++ | +++ | +++ | +++ | +++ |
- NCX | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
The levels of iron transporter and regulatory proteins | |||||||
- DMT1 | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
- ZIP14 | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
- Hepcidin | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
- Ferroportin | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
