Table 3 CNV analysis of 50 cancer genes in the patient primary tumour versus MUG-Myx2a and MUG-Myx2b cell lines.
From: Establishment of a novel cellular model for myxofibrosarcoma heterogeneity
Gene symbol | Chromosome | Tumor tissue | MUG-Myx2a | MUG-Myx2b |
|---|---|---|---|---|
ABL1 | chr9 | 0.9192 | 0.9438 | 1.0374 |
AKT1 | chr14 | 0.4480 | 1.0000 | 1.3372 |
ALK | chr2 | 1.1441 | 1.6414 | 1.6716 |
APC | chr5 | 1.0856 | 0.9466 | 0.9630 |
ATM | chr11 | 0.8256 | 0.8087 | 0.9741 |
BRAF | chr7 | 1.0480 | 1.5278 | 1.5718 |
CDH1 | chr16 | 1.0275 | 0.8986 | 0.8811 |
CDKN2A | chr9 | 0.1051 | NA | NA |
CSF1R | chr5 | 0.8576 | 0.8666 | 0.8804 |
CTNNB1 | chr3 | 0.9304 | 1.3203 | 1.4344 |
EGFR | chr7 | 1.3430 | 1.4048 | 1.6639 |
ERBB2 | chr17 | 1.0767 | 1.1440 | 1.5046 |
ERBB4 | chr2 | 1.0075 | 1.1100 | 1.0886 |
EZH2 | chr7 | 1.0183 | 0.9342 | 1.0099 |
FBXW7 | chr4 | 0.9910 | 1.0970 | 0.8166 |
FGFR1 | chr8 | 2.2310 | 2.6211 | 2.3104 |
FGFR2 | chr10 | 0.9797 | 1.1420 | 0.8278 |
FGFR3 | chr4 | 1.0820 | 0.5976 | 0.9027 |
FLT3 | chr13 | 0.8371 | 0.9192 | 1.3178 |
GNA11 | chr19 | 1.1316 | 1.1151 | 1.6261 |
GNAQ | chr9 | 0.9312 | 0.9096 | 1.2227 |
GNAS | chr20 | 0.7208 | 1.2971 | 1.5973 |
HNF1A | chr12 | 0.8146 | 1.0399 | 1.4925 |
HRAS | chr11 | 1.5547 | 1.4537 | 1.1087 |
IDH1 | chr2 | 1.2772 | 0.7513 | 0.8040 |
IDH2 | chr15 | 0.9802 | 1.0735 | 1.3360 |
JAK2 | chr9 | 0.8101 | 1.1047 | 0.8251 |
JAK3 | chr19 | 1.0752 | 2.0590 | 2.0163 |
KDR | chr4 | 0.7415 | 0.5758 | 0.9654 |
KIT | chr4 | 1.0669 | 0.8604 | 1.1048 |
KRAS | chr12 | 1.2703 | 2.1689 | 1.4992 |
MET | chr7 | 1.3360 | 1.7628 | 1.6280 |
MLH1 | chr3 | 0.1939 | NA | NA |
MPL | chr1 | 0.7063 | 0.9830 | 1.3276 |
NOTCH1 | chr9 | 1.1330 | 1.2689 | 1.4291 |
NPM1 | chr5 | 0.7543 | 1.1765 | 0.9742 |
NRAS | chr1 | 1.0851 | 2.2651 | 2.3976 |
PDGFRA | chr4 | 1.2816 | 1.1329 | 1.1979 |
PIK3CA | chr3 | 1.1218 | 1.0355 | 0.7826 |
PTEN | chr10 | 1.0146 | 1.0984 | 0.7667 |
PTPN11 | chr12 | 0.9374 | 1.1896 | 1.4320 |
RB1 | chr13 | 0.7520 | 0.7366 | 1.0491 |
RET | chr10 | 0.7390 | 1.0544 | 1.1011 |
SMAD4 | chr18 | 1.0836 | 1.4800 | 1.3592 |
SMARCB1 | chr22 | 1.1673 | 1.3899 | 1.6396 |
SMO | chr7 | 1.4613 | 1.3363 | 1.8677 |
SRC | chr20 | 1.1173 | 1.1082 | 1.4421 |
STK11 | chr19 | 1.6188 | 1.6498 | 1.7545 |
TP53 | chr17 | 1.2487 | 1.7442 | 1.8102 |
VHL | chr3 | 0.5489 | 0.6544 | 0.4328 |
