Table 4 Multivariate Cox regression analysis for cancer-specific survival.
From: Tumor Wide Horizontal Invasion Predicts Local Recurrence for Scrotal Extramammary Paget’s Disease
Variables | HR | 95%CI | Pf | |
|---|---|---|---|---|
Age | (<70 years/≥70years) | 0.001 | 0.000–3.227E25 | 0.844 |
Delay in diagnosis | (<7years/≥7years) | 0.000 | 0.000–1.182E55 | 0.900 |
Recurrence disease | (Absent/Present) | 0.002 | 0.000–4.094E47 | 0.915 |
Tumor size | (≤25 cm2/>25 cm2) | 1.196 | 0.054–26.693 | 0.910 |
Multiple lesions | (Absent/Present) | 0.001 | 0.000–3.142E48 | 0.904 |
Nodule formation | (Absent/Present) | 0.161 | 0.000–2.942E54 | 0.978 |
Lymphovascular invasion | (Absent/Present) | 1.397E16 | 0.000–1.21E111 | 0.739 |
Adnexa invasion | (Absent/Present) | 0.000 | 0.000–2.219E18 | 0.686 |
Wide horizontal invasion | (≤2.0 cm/>2.0 cm) | 1.191 | 0.034–41.951 | 0.923 |
Invasion level | — | — | 0.473 | |
In situ | 1 | — | — | |
Micro-invasion | 0.001 | 0.000–2.945E65 | 0.933 | |
Deep invasion | 10.742 | 0.237–486.051 | 0.222 | |
Lymph node metastasis | (Absent/Present) | 0.000 | 0.000–2.463E75 | 0.807 |
p53 expression | — | — | 0.045* | |
Negative | 1 | — | — | |
Low expression | 0.591 | 0.033–10.508 | 0.720 | |
High expression | 152.280 | 1.665–1.393E4 | 0.029 | |
Ki67 expression | (<20%/≥20% positive) | 0.554 | 0.021–14.446 | 0.723 |
