Table 1 Carbamazepine-induced Stevens-Johnson syndrome (CBZ-SJS) cases and tolerant controls without HLA-B*15:02.

From: HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis

Study (Region)

CBZ-SJS cases

Tolerant controls

Total

Cases without HLA-B*15:02

HLA-B genotype of cases without HLA-B*15:02a

Total

Controls without HLA- B*15:02

Tassaneeyakul, 2010 (Thailand)3

42

5

(1) 18:01/56:04

(2) 15:21/48:01

(3) 27:06/56:01

(4) 15:21/40:01

(5) 15:11/46:01

42

37

Cheung, 2013 (Hong Kong)4

26

2

(1) 13:01/54:01

(2) 13:01/15:01

135

119

Khor, 2014 (Malaysia)5

5

3

(1) 15:08/56:01

(2) 15:01/41:01

(3) 40:06/51:06

52

50

Nguyen, 2015 (Vietnam)6

35

3

(1) 13:01/46:01

(2) 51:02/54:01

(3) 38:02/51:02

25

19

Total

108

13

 

254

225

  1. The data was obtained from available studies in Asian populations with known associations between HLA-B*15:02 and CBZ-SJS.
  2. aUnderlined alleles represented members of the HLA-B75 serotype.
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