Figure 1: Systolic blood pressure, renal ultrasound analysis, renal function, proteinuria, and sodium metabolism in DS rats. | Scientific Reports

Figure 1: Systolic blood pressure, renal ultrasound analysis, renal function, proteinuria, and sodium metabolism in DS rats.

From: Multiple Mechanisms are Involved in Salt-Sensitive Hypertension-Induced Renal Injury and Interstitial Fibrosis

Figure 1

(a) SBP was elevated in DS rats fed the 8% salt diet compared with those fed the 0.3% salt diet or those treated with HCTZ. (b) The graph represents the renal RI. The RI was calculated as (a,b)/a, where “a” is the peak systolic velocity, and “b” is the end diastolic velocity. (c) Creatinine clearance decreased beginning at week nine on a high salt diet. (d) The high salt diet increased protein excretion starting at week three. (e) At 6 weeks, serum albumin was significantly decreased in the DSH group compared with the DSN group, and HCTZ treatment improved this change. (f) The graph shows Na+ excretion in urine, which was increased by HCTZ treatment. (g–i) Representative images of the renal resistive index (RI) measurements for each group. Pulsed Doppler ultrasounds were obtained for the intra-renal artery of the renal cortex. *p < 0.05, **p < 0.01 versus DSN group. #p < 0.05, ##p < 0.01: DSH + HCTZ group versus DSH group.

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