Figure 7

Structural aspects of Lapatinib-Lapatinib Interactions: (A) Molecular Structure showing pkas values for amine groups Interactions; (B) Unit cell of Lapatinib free base form I; (C) Close up of N14−H—O3 hydrogen bond; (D) Close up of the closest distances for Carbon-Carbon pairs; (E) Close up of the closest distances for Nitrogen-Carbon pairs.