Table 1 Different NP formulations prepared using HSA.

From: Development and Pre-Clinical Evaluation of Recombinant Human Myelin Basic Protein Nano Therapeutic Vaccine in Experimental Autoimmune Encephalomyelitis Mice Animal Model

Formula

Solvent

PCL (mg)

MW PVA (Da)

% PVA (w/v)

Volume of PVA (mL)

Amount of protein (mg)

F1

Acetone

100

31,000

2

50

50

F2

DCM

100

31,000

2

50

50

F3

DCM

100

31,000

2

10

50

F4

DCM

100

31,000

4

10

50

F5

DCM

100

6,000

2

10

50

F6

DCM

100

88,000

2

10

50

F7

DCM

100

31,000

2

10

100

F8

DCM

200

31,000

2

10

50

F9

DCM

400

31,000

2

10

50

  1. PCL: poly(ε-caprolactone); PVA: polyvinyl alcohol; DCM: dichloromethane; HSA: human serum albumin.