Figure 3 | Scientific Reports

Figure 3

From: Elevated circulating levels of the interferon-γ–induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still’s disease

Figure 3

CXC chemokine 9 (CXCL9) (A,B,C,D), CXCL10 (E,F,G,H) and CXCL11 (I,J,K,L) expression in skin biopsies of healthy controls (A,E,I), adult-onset Still’s disease (AOSD) (B,F,J), eczema (C,G,K) and psoriasis (D,H,L) patients. Original magnification, ×200. Note that the percentages of CXCL9- and CXCL10-positive cells are low. However, CXCL9 and CXCL10 were more frequently expressed in the skin of AOSD patients than that of eczematous dermatitis and psoriasis patients. Conversely, CXCL11 was more frequently expressed in the skin of eczematous dermatitis and psoriasis patients than that of AOSD patients. Black arrow: epidermis; red arrow: dermoepidermal junction; blue arrow: pilosebaceous unit.

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