Table 1 Genotypes on the OXTR, CD38, and AVPR1a genes included in the Cumulative Genetic Risk Index

From: Affiliation buffers stress: cumulative genetic risk in oxytocin–vasopressin genes combines with early caregiving to predict PTSD in war-exposed young children

 

Genotype

Prevalence of high-risk genotype

 

High risk

Low risk

Child

Mother

Father

OXTR rs1042778

TT

GG, GT

11.5%

7.7%

8.1%

OXTR rs2254298

GG

AA, AG

42.6%

43.0%

41.8%

OXTRrs53576

AA, AG

GG

44.3%

44.4%

40.0%

CD38 rs3796863

CC

AA, AC

33.6%

32.8%

37.4%

AVPR1A RS3

327 bpa

Non-327

22.6%

14.5%

20.4%

Cumulative risk mean (s.d.)

  

1.56 (1.18)

1.42 (1.10)

1.56 (1.09)

Correlations

  

Child–mother: r=0.53***

Child–father, r=0.42***

Mother–father: r=0.19**

  1. Note: cumulative genetic risk is computed for each family member by combining the number of high-risk genotypes on each of the five single-nucleotide polymorphisms.
  2. **P<0.01, ***P<0.001.
  3. At least one 327-bp repeat.
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