Table 5 List of top 10 significant pathways for GC2
From: Genetic association of impulsivity in young adults: a multivariate study
Pathways | P-value | q-value |
|---|---|---|
KEGG pathways | ||
Arrhythmogenic right ventricular cardiomyopathy | 1.2 × 10−23 | 2.3 × 10−21 |
Pathways in cancer | 2.2 × 10−19 | 2.2 × 10−17 |
Focal adhesion | 4.2 × 10−19 | 2.7 × 10−17 |
Dilated cardiomyopathy | 1.6 × 10−17 | 6.9 × 10−16 |
MAPK signaling | 1.7 × 10−17 | 6.9 × 10−16 |
Hypertrophic cardiomyopathy | 3.1 × 10−17 | 1.0 × 10−15 |
Calcium signaling | 4.3 × 10−17 | 1.2 × 10−15 |
PI3K-Akt signaling | 2.7 × 10−13 | 6.8 × 10−12 |
Vascular smooth muscle contraction | 1.5 × 10−11 | 3.4 × 10−10 |
Long-term depression | 5.8 × 10−11 | 1.1 × 10−09 |
GeneGo pathways | ||
Signal transduction_Activation of PKC via G-protein-coupled receptor | 1.0 × 10−09 | 6.3 × 10−07 |
Immune response_Fc epsilon RI | 2.5 × 10−08 | 6.1 × 10−06 |
Immune response_CD28 signaling | 3.1 × 10−08 | 6.1 × 10−06 |
Immune response_CCR5 signaling in macrophages and T lymphocytes | 4.8 × 10−08 | 7.0 × 10−06 |
Neurophysiological process_Long-term depression in cerebellum | 7.2 × 10−08 | 8.4 × 10−06 |
Immune response_NFAT in immune response | 1.1 × 10−07 | 1.0 × 10−05 |
Immune response_T cell receptor signaling | 1.7 × 10−07 | 1.4 × 10−05 |
Neurophysiological process_NMDA-dependent postsynaptic long-term potentiation in CA1 hippocampal neurons | 2.6 × 10−07 | 1.9 × 10−05 |
Glutamate regulation of dopamine D1A receptor signaling Glutamate regulation of Dopamine D1A receptor signaling | 3.1 × 10−07 | 2.0 × 10−05 |
Ca(2+)-dependent NF-AT signaling in cardiac hypertrophy | 3.7 × 10−07 | 2.1 × 10−05 |
