Table 1 Baseline demographic characteristics by treatment arm

	Active (N=22)		Placebo (N=20)		t-test of group differences (N=42)
	Mean	95% CI	Mean	95% CI	t	P
Age	49.42	42.14–56.70	43.28	37.41–49.14	1.61	0.12
BMI	29.98	27.82–33.84	30.04	27.44–35.16	−0.19	0.85
Fasting plasma glucose^a	97.25	90.71–103.40	96.90	93.82–102.57	0.10	0.92
Leukocyte telomere length^a	0.87	0.79–0.95	0.99	0.93–1.08	−2.48	0.02
HOMA^a	3.14	2.00–3.58	3.11	2.45–4.38	0.05	0.96
Oral glucose tolerance test^a	103.88	91.23–110.62	131.6	107.07–166.43	−2.07	0.05
Baseline HDRS-21	16.73	14.60–19.93	14.55	8.25–14.09	1.43	0.16

Abbreviations: BMI, body mass index; CI, confidence interval.
^aMissing data were imputed using fully conditional specification regression. ^bBolded values significant at P<0.05.

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