Figure 4
From: Allergic fetal priming leads to developmental, behavioral and neurobiological changes in mice
Measures of locomotor activity, memory formation and anxiety. No differences were observed in (a) the total distance traveled or (b) average velocity between treatment groups during the open-field observations. (c) Mice from both MAA- and PBS-exposed dams showed normal object recognition as measured by a preference (that is, >50% sniffing) for a novel versus familiar object. (d) There were no differences observed in the percent of time spent in the open arms of the elevated plus maze arena between treatment groups. (e) Similarly, no differences were observed in the total number of entries into the open arm between offspring of PBS-treated and MAA dams. (f) These similarities parallel similarities in the total number of entries into all arms of the maze, an internal control for locomotor activity. MAA, maternal allergic asthma; PBS, phosphate-buffered saline.
