Figure 1

Markers of endothelial damage in blood samples. Bar diagrams showing in vivo levels of markers of endothelial damage: circulating endothelial cells (CEC) and endothelial progenitor cells (EPC) in whole blood samples (a, b), and von Willebrand factor (VWF) and soluble vascular cell adhesion molecule-1 (sVCAM-1) in plasma samples (c, d). Graphs show levels of these markers in healthy controls (CON) and in major depression patients at the moment of diagnosis (MD-0), and after 8 and 24 weeks of antidepressant treatment (MD-8 and MD-24) with the selective serotonin reuptake inhibitor escitalopram. Results are expressed as mean±s.e.m. (n=12). *P<0.01 versus CON; #P<0.05 versus MD-0; §P<0.05 versus MD-8.