Table 1 Demographic and clinical characteristics of patient samples

From: Endothelial damage in major depression patients is modulated by SSRI treatment, as demonstrated by circulating biomarkers and an in vitro cell model

Variable

Value (n=12)

Sex (% men)

41.7

Age at first episode (years)

46.5±9.8

Number of previous episodes

0.4±0.7

Index episode

 Age (years)

49.6±10.5

 Duration of episode (months)

5.0±2.1

 MD-0 HDRS score

26.5±4.2#

 MD-8 HDRS score

9.1±5.2*#

 MD-24 HDRS score

3.2±4.2*#

Healthy controls

 Sex (% men)

41.7

 Age (years)

48.0±8.5

 HDRS score

0.59±1.2

  1. Abbreviations: CON, controls; HDRS score, Hamilton Depression Rating Scale-17 items; MD-0, major depression patients at the moment of diagnosis; MD-8 and MD-24, major depression patients during antidepressant treatment with escitalopram for 8 and 24 weeks
  2. Values are expressed as mean±s.d. (n=12). *P<0.001 versus MD-0, #P<0.05 versus CON.