Table 1 GVs with the lowest or highest variability in the five ethnic populations

From: Variability of 128 schizophrenia-associated gene variants across distinct ethnic populations

GWAS rank

Index SNP

Chr

 

MAF

Variability index

    

EAS

EUR

AFR

AMR

SAS

 

GVs with the lowest variability

 35

rs36068923

8

G

0.189

0.192

0.256

0.183

0.194

1.07

 28

chr3_180594593_I

3

I

0.170

0.218

0.316

0.183

0.257

1.34

 128

chr5_140143664_I

5

I

0.473

0.467

0.689

0.435

0.481

1.43

 62

chr2_146436222_I

2

I

0.095

0.185

0.163

0.101

0.096

1.60

 97

rs12148337

15

T

0.534

0.482

0.729

0.483

0.529

1.67

 88

rs7819570

8

T

0.103

0.199

0.261

0.120

0.197

1.73

 93

rs832187

3

C

0.532

0.402

0.676

0.370

0.370

1.75

 68

rs77149735

1

A

0

0.022

0.004

0.010

0.003

1.85

 84

rs1106568

4

G

0.267

0.250

0.341

0.206

0.416

1.99

 122

rs7267348

20

C

0.238

0.267

0.388

0.291

0.257

1.99

GVs with the highest variability

 42

rs7432375

3

A

0.791

0.435

0.041

0.594

0.508

9.46

 44

rs111294930

5

G

0.004

0.281

0.013

0.285

0.300

8.65

 83

rs59979824

2

A

0.412

0.336

0.023

0.458

0.242

7.98

 114

rs12421382

11

T

0.232

0.344

0.017

0.398

0.206

7.45

 34

rs9607782

22

A

0.056

0.265

0.152

0.497

0.327

7.44

 45

rs2973155

5

T

0.596

0.359

0.079

0.460

0.493

7.23

 11

rs4702

15

G

0.475

0.437

0.059

0.411

0.501

7.14

 22

rs12129573

1

A

0.203

0.397

0.108

0.542

0.321

7.03

 18

rs11693094

2

T

0.500

0.422

0.061

0.429

0.404

7.02

 12

rs75968099

3

T

0.055

0.363

0.060

0.323

0.321

6.96

  1. Abbreviations: AFR, African; AMR, American; Chr, chromosome; EAS, East Asian; EUR, European; GV, genetic variant; GWAS, genome-wide association study; I, insertion; MAF, minor allele frequency; SAS, South Asian; SNP, single-nucleotide polymorphism.