Table 4 Hippocampal transcript levels in WLIs and WMIs in response to EE

From: Nature and nurture: environmental influences on a genetic rat model of depression

Gene

WLI ΔCt±s.e.m.

WMI ΔCt±s.e.m.

 

Control

EE

Control

EE

Adcy3

8.21±0.05

8.54±0.08**

8.26±0.04

8.54±0.06**

Amfr

3.13±0.06

3.18±0.07

3.27±0.05

3.27±0.09

Atp11c

7.83±0.15

8.04±0.22

7.74±0.14

7.69±0.13

Cd59

5.39±0.08

5.44±0.10

5.49±0.06

5.41±0.08

Cadm1

3.13±0.06

3.28±0.08

3.17±0.10

3.45±0.07*

Cdr2

9.50±0.20

8.83±0.24

9.25±0.11

8.82±0.19

Cmas

6.38±0.11

6.36±0.19

6.30±0.11

6.47±0.14

Dgka

7.25±0.09

6.72±0.09**

6.85±0.10

6.69±0.02

Fam46a

10.63±0.12

10.50±0.18

10.07±0.14

10.29±0.17

Irf3

8.66±0.17

7.93±0.17*

7.92±0.18

7.55±0.17

Kiaa1539

7.20±0.07

6.67±0.10**

6.98±0.07

6.64±0.09**

Marcks

4.76±0.06

4.90±0.08

5.02±0.04

4.92±0.13

Psme1

7.49±0.12

7.13±0.10+

7.34±0.11

7.05±0.11

Raph1

5.48±0.06

5.00±0.08**

5.34±0.10

5.24±0.10

Tlr7

9.63±0.14

10.44±0.17*

9.97±0.22

10.05±0.17

  1. Abbreviations: EE, environmental enrichment; WLI, Wistar Kyoto Less Immobile; WMI, Wistar Kyoto More Immobile.
  2. Please note that the ΔCt values relate to relative concentration by 2−ΔCT.
  3. *P<0.05, **P<0.01 by Bonferroni post hoc after significant two-way analysis of variance (strain × environment). Comparisons are within strain and between control and EE.
  4. +P<0.05 by Student’s t-test. Comparisons are within strain and between control and EE.
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