Figure 3

Riluzole increases inhibition in the prefrontal cortex of the autism spectrum disorder (ASD) group only. Riluzole increased the inhibitory index in the ASD group, not controls: *Drug × group interaction; F(1, 24)=4.288, P<0.05. Post-hoc analyses demonstrate a significant difference between groups in the change in inhibitory index after riluzole administration: ANCOVA; F(1, 27)=4.290, P<0.05. Results are expressed as mean (±s.e.m.) and are corrected for State anxiety score.