Figure 2

The period length of Bmal1-luc rhythm (in vitro period) in the control, DSWPD and N24SWD groups. (a) In vitro periods in 50 control fibroblast samples (open circle), 41 DSWPD fibroblast samples (blue circle) and 26 N24SWD fibroblast samples (red circle). Triangles represent mean in vitro periods in the control group (open), DSWPD group (blue) and N24SWD group (red). Data are presented as mean±s.d.; *P<0.05; **P<0.01. (b) Frequency distribution of in vitro period in control fibroblast samples (open bar), DSWPD fibroblast samples (blue bar) and N24SWD fibroblast samples (red bar). Each bin represents a 0.5 h period. DSWPD, delayed sleep–wake phase disorder; N24SWD, non-24-hour sleep–wake rhythm disorder.