Table 1 Results from multivariate analysis for 30 probe sets within the thiopurine pathway

From: Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics

Probe set

Gene

P-value for interaction effect

P-value for expression main effect

203939_at

NT5E

0.395

0.048

203672_x_at

TPMT

0.092

0.047

1553995_a_at

NT5E

0.331

0.016

204169_at

IMPDH1

0.0002a

0.521

209440_at

PRPS1

0.0008a

0.735

212379_at

GART

0.033

0.874

226363_at

ABCC5

0.049

0.705

  1. Probe sets with effects with P-value <0.05 are displayed.
  2. aStatistically significant after adjusting for multiple testing within the pathway (Bonferroni threshold of 0.002).
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