Figure 3
From: The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness
(a) CG-137 methylation correlates negatively with the GH-induced increment in growth rate in 136 children treated with GH (R=−0.50, P=2.7 × 10−10); (b) CG-137 methylation correlates negatively with the GH-induced increment in serum IGF1 concentration in children treated with GH R=−0.52, P=1.7 × 10−10).
