Table 2 General linear model for regression of sex, age, GH dose and CG-137 methylation on increment in growth rate (cm per year) induced by GH treatment
From: The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness
Estimates | s.e. | t-value | Pr(>|t|) | |
|---|---|---|---|---|
Intercept | 13.21 | 1.7 | 7.8 | 2 × 10-12 |
Age at GH onset (years) | 0.13 | 0.05 | 2.46 | 0.015 |
Sex | 0.03 | 0.28 | 0.12 | 0.91 |
GH dose (mg kg−1 per week) | 0.014 | 6.7 × 10−3 | 2.04 | 0.04 |
CG-137 methylation (%) | −0.22 | 0.032 | −6.8 | 4 × 10−10 |
