Table 1 Classification table comparing test outcome with true agranulocytosis status

From: Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosis

Test result

Agranulocytosis

Total

 

Yes

No

 

Positive: High risk

a=sk

b=x-sk

a+b=x

Negative: Low risk

c=(1-s) k

d=1-x-(1-s) k

c+d=1-x

Total

a+c=k

b+d=1-k

1

  1. Cell probabilities are expressed in terms of sensitivity (s) and size of the HR group (x).
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