Research Highlights in 2024

Astrocytes: emerging stars of engrams

• Sofiya Zbaranska
• Sheena A. Josselyn

Tug of war between phosphatase and kinase during sleep

• Niels Niethard
• Jan Born

Triaptosis: an endosome-dependent cell death modality

• Daolin Tang
• Rui Kang
• Guido Kroemer

Encoding immune responses: the moonlighting function of alanyl-tRNA synthetase

• Pin Wang
• Xiaoyu Hu

Stressing out the intestinal microbiota via a brain-neuroglandular circuit

• Wen Zhang
• David Artis

A GSDMD agonist boosts specific antitumor immunity

• Yingying Zhang
• Jiahuai Han

A cross-species foundation model for single cells

• Korbinian Traeuble
• Matthias Heinig

Nucleophagy repairs toxic DNA lesions

• Ines Tomaskovic
• Cristian Prieto-Garcia
• Ivan Dikic

Immunity hubs orchestrating antiviral defense

• Linnan Zhu
• Zemin Zhang

Fine-tuning protein hunger: sex- and mating-dependent setpoint control

• Yangkyun Oh
• Won-Jae Lee

Knowing when to stop: MICL self-regulates neutrophil NETosis

• Hanjoo Brian Shim
• Justin François Deniset
• Paul Kubes

Fueling metabolic adaptation: lysosomal AMPK ignites glutaminolysis

• Benoit Viollet
• Bruno Guigas

Feeling the danger: local wound signaling in plants

• Lukas Hoermayer
• Jiří Friml

Lysine methylation steps into another step of the central dogma

• Zuodong Zhao
• Bing Zhu

tRNA repair: the key to thermo-sensitive male sterility in rice

• Nai-Qian Dong
• Hong-Xuan Lin

Designing de novo D-protein binders

• Haiyan Liu

PDK1 neddylation by Smurf1 drives Akt activation

• Rajesh Kumar Manne
• Rajni Kant
• Hui-Kuan Lin

Illuminating nucleosome interactions

• Silvija Bilokapic
• Mario Halic

Preservation of a youthful path to evergreen platelets?

• Sten Eirik W. Jacobsen

Stroke-induced trained immunity spells bad news for the heart

• George Hajishengallis
• Triantafyllos Chavakis