Volume 26 Issue 12, December 2019

Cover legend: Cellular tropism of Adeno-Associated Virus vector AAVrh10 in the rat retina. Eyes were injected intravitreally with AAVrh10-CMV-EGFP at a dose of 2.5e12 vector genomes/eye. Retinal sections were counter-stained with GFP and parvalbumin antibodies. GFP-positive cells, transduced by AAVrh10 vector, show green fluorescence. Parvalbumin-positive cells (a subgroup of amacrine and ganglion cells) show red fluorescence. AAVrh10 vector-transduced amacrine and ganglion cells show yellow fluorescence. Cell nuclei were visualized by DAPI staining (blue). See article by Zeng et al in the September 2019 issue of Gene Therapy.