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This Perspective argues that tissue-manufacturing approaches relying on directed self-organization will enable the production of functional tissues with complex biological features.
This Perspective discusses recent technological developments in flow cytometry and DNA sequencing that enable the interrogation of T-cell specificities in infection, cancer and autoimmunity to inform disease development and treatment.
This Perspective puts forward the concept of medical-device-on-a-chip, that is, a microphysiological system that leverages organ-on-a-chip technology for the development and testing of medical devices.
Drawing from recent successes in cancer immunotherapy, this Perspective discusses that effective cancer-nanomedicine therapies can be designed to prime antitumour immunity far from the site of disease.
