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Beltran and colleagues discuss the challenges in treating metastatic prostate cancer and strategies to accelerate precision oncology and improve therapy and clinical decisions in this setting.
Aguirre-Ghiso and colleagues discuss the current status of the cancer dormancy field, including challenges and opportunities for monitoring and targeting dormant cancer.
Bozic and Wu discuss how quantitative mathematical models elucidate the various stages of tumor evolution, from premalignancy to malignant progression, and the response to therapy.