Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Despite sharing common features with the helix–turn–helix family of transcription factors, ribbon–helix–helix proteins recognize different operator sequences, bind to both symmetric and asymmetric DNA sites, bend DNA by varying amounts and make unique protein–protein interactions to stabilize their complexes with DNA.
Mathematical models of infectious disease dynamics are valuable tools for understanding the dynamics of outbreaks and designing effective interventions. Focusing on community-acquired meticillin-resistantStaphylococcus aureusas a case study, the authors explain how to construct and apply a simple transmission model of an emerging pathogen.
