Brief Communications in 2021

p53-mediated AKT and mTOR inhibition requires RFX7 and DDIT4 and depends on nutrient abundance

• Luis Coronel
• David Häckes
• Martin Fischer

NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity

• Kelley Ingram
• Shiela C. Samson
• Michelle C. Mendoza

Lineage-restricted neoplasia driven by Myc defaults to small cell lung cancer when combined with loss of p53 and Rb in the airway epithelium

• Jasmine Chen
• Aleks Guanizo
• Daniel J. Gough

CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis

• Dina Polosukhina
• Kshipra Singh
• Lori A. Coburn

P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis

• Ming Zhu
• Ruiqing Peng
• Guocan Wang

Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy

• Audrey Lequeux
• Muhammad Zaeem Noman
• Bassam Janji

Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair

• Josune Alonso-Marañón
• Alberto Villanueva
• Lluís Espinosa

Application of machine learning to large in-vitro databases to identify cancer cell characteristics: telomerase reverse transcriptase (TERT) expression

• Jeff Sherman
• Grant Verstandig
• Yisroel Brumer

Cell surface GRP78 and Dermcidin cooperate to regulate breast cancer cell migration through Wnt signaling

• Tyson W. Lager
• Clay Conner
• Athanasia D. Panopoulos

Application of machine learning to large in vitro databases to identify drug–cancer cell interactions: azithromycin and KLK6 mutation status

• Jeff Sherman
• Grant Verstandig
• Yisroel Brumer

Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis

• Daisy Flores Rangel
• Louis Dubeau
• Amy S. Lee

Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein

• Jacqueline Bernardino-Sgherri
• Capucine Siberchicot
• Anne Bravard

Overexpression of Hmga2 activates Igf2bp2 and remodels transcriptional program of Tet2-deficient stem cells in myeloid transformation

• Jie Bai
• Takako Yokomizo-Nakano
• Goro Sashida