Bilateral adrenocortical hyperplasias (BAHs) are one cause of adrenocorticotropin-independent Cushing's syndrome. Until recently BAHs were relatively unknown and thought to be infrequent. This article reviews the molecular genetics of adrenocortical tumor development with an emphasis on BAHs. It also suggests a classification for BAHs that is based on their genetics and histology.
- Constantine A Stratakis
- Sosipatros A Boikos