Nature Search

N-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells

D Del Bufalo
C Leonetti
G Zupi
Research01 Jan 1998
British Journal of Cancer

Volume: 77, P: 210-215
Guadecitabine plus ipilimumab in unresectable melanoma: five-year follow-up and integrated multi-omic analysis in the phase 1b NIBIT-M4 trial

The NIBIT-M4 trial was designed to assess the safety, biological and clinical activity of anti-CTLA4 ipilimumab with the DNA hypomethylating agent guadecitabine in advanced melanoma patients. Here the authors report the five-year follow-up results of the trial and an integrated multi-omics analysis of pre- and on-treatment tumor biopsies.

Teresa Maria Rosaria Noviello
Anna Maria Di Giacomo
Michele Ceccarelli
ResearchOpen Access22 Sept 2023
Nature Communications

Volume: 14, P: 1-18
HLA-DQ_β gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

John A. Todd
John I. Bell
Hugh O. McDevitt
Research21 Oct 1987
Nature

Volume: 329, P: 599-604
Mutually exclusive NRAS^Q61R and BRAF^V600E mutations at the single-cell level in the same human melanoma

M Sensi
G Nicolini
A Anichini
Research06 Feb 2006
Oncogene

Volume: 25, P: 3357-3364
Alignment of radio and optical orientations in high-redshift radio galaxies

K. C. Chambers
G. K. Miley
W. van Breugel
Research21 Oct 1987
Nature

Volume: 329, P: 604-606
Genomic landscape of diffuse glioma revealed by whole genome sequencing

The genomic landscape of diffuse gliomas remains to be characterised. Here, the authors perform whole genome sequencing of 403 tumours and identify recurrent coding and non-coding genetic mutations, their associations with clinical outcomes and potential therapeutic targets.

Ben Kinnersley
Josephine Jung
Keyoumars Ashkan
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-18
Allostimulation of patients' lymphocytes generates both T and NK-like cells cytotoxic for autologous melanoma

A Balsari
G Fossati
G Parmiani
Research01 Jul 1985
British Journal of Cancer

Volume: 52, P: 73-80
Enrichment of CD56^dimKIR+CD57+ highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients

The role of NK cells in tumour lymphatics is poorly understood. Here, the authors show that the tumour cell-infiltrated lymph nodes of melanoma patients have an altered cytokine milieu and contain an expanded population of NK cells with high tumour-cytotoxic activity.

Talib Hassan Ali
Simona Pisanti
Ennio Carbone
Research04 Dec 2014
Nature Communications

Volume: 5, P: 1-9
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Understanding the molecular events controlling melanoma progression are necessary to find improved therapeutics. Here, the authors report oncogenic SOX2-GLI1 transcriptional complex to drive melanoma invasion through the induction of the sialyltransferase ST3GAL1, and report ST3GAL1-AXL axis as driver of melanoma metastasis.

Silvia Pietrobono
Giulia Anichini
Barbara Stecca
ResearchOpen Access17 Nov 2020
Nature Communications

Volume: 11, P: 1-18
Heme catabolism by tumor-associated macrophages controls metastasis formation

Tumor-associated macrophages (TAMs) play multifaceted roles in establishing an immunosuppressive tumor microenvironment. Sica and colleagues find that macrophage-intrinsic complement signaling initiates a pathway leading to the induction of highly tumorigenic TAMs.

Francesca Maria Consonni
Augusto Bleve
Antonio Sica
Research26 Apr 2021
Nature Immunology

Volume: 22, P: 595-606
Interleukin-2 gene-transduced human leukemic cells induce major histocompatibility complex-restricted and -unrestricted anti-leukemic effectors in mixed lymphocyte-tumor cultures

Alessandro Cignetti
Anna Guarini
Robert Foa
Research24 May 2000
Cancer Gene Therapy

Volume: 7, P: 167-176
IL2 treatment for cancer: from biology to gene therapy

R Foa
A Guarini
B Gansbacher
Reviews01 Dec 1992
British Journal of Cancer

Volume: 66, P: 992-998
Cancer vaccines

A G Dalgleish
ReviewsOpen Access21 Apr 2000
British Journal of Cancer

Volume: 82, P: 1619-1624
A phase I trial of repeated tumour-infiltrating lymphocyte (TIL) infusion in metastatic melanoma

A Ravaud
E Legrand
N Gualde
Research01 Feb 1995
British Journal of Cancer

Volume: 71, P: 331-336
Expression of fibronectin, fibronectin isoforms and integrin receptors in melanocytic lesions

PG Natali
MR Nicotra
A Bigotti
Research01 Jun 1995
British Journal of Cancer

Volume: 71, P: 1243-1247
Decreased adhesion to endothelial cells and matrix proteins of H-2K^b gene transfected tumour cells

D Lauri
C De Giovanni
P-L Lollini
Research01 Nov 1993
British Journal of Cancer

Volume: 68, P: 862-867
Elevated pretreatment serum levels of soluble vascular cell adhesion molecule 1 and lactate dehydrogenase as predictors of survival in cutaneous metastatic malignant melanoma

A Franzke
M Probst-Kepper
J Atzpodien
Research01 Jul 1998
British Journal of Cancer

Volume: 78, P: 40-45
Expression of interleukin 6 (IL-6) correlates with oestrogen receptor in human breast carcinoma

G Fontanini
D Campani
F Basolo
ResearchOpen Access09 Apr 1999
British Journal of Cancer

Volume: 80, P: 579-584
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair

Marco Tartaglia and colleagues report the identification of mutations of SHOC2 in individuals with Noonan-like syndrome with loose anagen hair. The mutations cause aberrantly acquired N-myristoylation of SHOC2 resulting in aberrant targeting of SHOC2 to the plasma membrane. SHOC2 is believed to function as a scaffold linking RAS to downstream signal transducers.

Viviana Cordeddu
Elia Di Schiavi
Marco Tartaglia
Research16 Aug 2009
Nature Genetics

Volume: 41, P: 1022-1026
An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells

Valentina Perotti
Paola Baldassari
Roberta Mortarini
ResearchOpen Access01 Feb 2019
Oncogene

Volume: 38, P: 4384-4396
Correction to: NFATc2 is an intrinsic regulator of melanoma dedifferentiation

V. Perotti
P. Baldassari
R. Mortarini
Amendments and CorrectionsOpen Access28 Jan 2019
Oncogene

Volume: 38, P: 3763-3764
Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade

E Lengyel
H Wang
D Boyd
Research29 May 1997
Oncogene

Volume: 14, P: 2563-2573
Does the emergence and persistence of donor-derived leukaemia-reactive cytotoxic T lymphocytes protect patients given an allogeneic BMT from recurrence? Results of a preliminary study

D Montagna
F Locatelli
R Maccario
Research09 Oct 1998
Bone Marrow Transplantation

Volume: 22, P: 743-750
Stimulation of urokinase-type plasminogen activator receptor expression by PMA requires JNK1-dependent and -independent signaling modules

R Gum
J Juarez
D Boyd
Research17 Jul 1998
Oncogene

Volume: 17, P: 213-225
Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder

M Milella
J Jacobelli
A Santoni
ResearchOpen Access29 Jan 1999
British Journal of Cancer

Volume: 79, P: 770-779
Metastatic potential of human melanoma cells in nude mice - characterisation of phenotype, cytokine secretion and tumour-associated antigens

D Schadendorf
I Fichtner
BM Henz
Research01 Jul 1996
British Journal of Cancer

Volume: 74, P: 194-199
Pooled peptides from HER-2/neu-overexpressing primary ovarian tumours induce CTL with potent antitumour responses in vitro and in vivo

A D Gritzapis
S A Perez
M Papamichail
ResearchOpen Access07 Dec 2004
British Journal of Cancer

Volume: 92, P: 72-79
Emerging perovskite monolayers

Metal-halide and oxide perovskites are a rich playground for fundamental studies and applications. This Review focuses on the opportunities opened by reducing the dimensionality of these materials to two-dimensional monolayers.

Antonio Gaetano Ricciardulli
Sheng Yang
Michael Saliba
Reviews10 Jun 2021
Nature Materials

Volume: 20, P: 1325-1336
Perifosine and sorafenib combination induces mitochondrial cell death and antitumor effects in NOD/SCID mice with Hodgkin lymphoma cell line xenografts

S L Locatelli
A Giacomini
C Carlo-Stella
Research30 Jan 2013
Leukemia

Volume: 27, P: 1677-1687
NFATc2 is an intrinsic regulator of melanoma dedifferentiation

V Perotti
P Baldassari
R Mortarini
Research21 Sept 2015
Oncogene

Volume: 35, P: 2862-2872
Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma

G Grazia
C Vegetti
A Anichini
ResearchOpen Access02 Oct 2014
Cell Death & Disease

Volume: 5, P: e1434
(Epi)genotype–phenotype correlations in Beckwith–Wiedemann syndrome

Alessandro Mussa
Silvia Russo
Giovanni Battista Ferrero
Research22 Apr 2015
European Journal of Human Genetics

Volume: 24, P: 183-190
BRAF alterations are associated with complex mutational profiles in malignant melanoma

Maria Daniotti
Maria Oggionni
Monica Rodolfo
Research14 Jun 2004
Oncogene

Volume: 23, P: 5968-5977
EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells

K Rea
M Sensi
A Tomassetti
ResearchOpen Access03 Oct 2013
Cell Death & Disease

Volume: 4, P: e815
BIM upregulation and ROS-dependent necroptosis mediate the antitumor effects of the HDACi Givinostat and Sorafenib in Hodgkin lymphoma cell line xenografts

S L Locatelli
L Cleris
C Carlo-Stella
Research24 Feb 2014
Leukemia

Volume: 28, P: 1861-1871
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib

D Lecis
C Drago
D Delia
ResearchOpen Access11 May 2010
British Journal of Cancer

Volume: 102, P: 1707-1716

Search

N-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells

Guadecitabine plus ipilimumab in unresectable melanoma: five-year follow-up and integrated multi-omic analysis in the phase 1b NIBIT-M4 trial

HLA-DQ_β gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

Mutually exclusive NRAS^Q61R and BRAF^V600E mutations at the single-cell level in the same human melanoma

Alignment of radio and optical orientations in high-redshift radio galaxies

Genomic landscape of diffuse glioma revealed by whole genome sequencing

Allostimulation of patients' lymphocytes generates both T and NK-like cells cytotoxic for autologous melanoma

Enrichment of CD56^dimKIR+CD57+ highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients

ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Heme catabolism by tumor-associated macrophages controls metastasis formation

Interleukin-2 gene-transduced human leukemic cells induce major histocompatibility complex-restricted and -unrestricted anti-leukemic effectors in mixed lymphocyte-tumor cultures

IL2 treatment for cancer: from biology to gene therapy

Cancer vaccines

A phase I trial of repeated tumour-infiltrating lymphocyte (TIL) infusion in metastatic melanoma

Expression of fibronectin, fibronectin isoforms and integrin receptors in melanocytic lesions

Decreased adhesion to endothelial cells and matrix proteins of H-2K^b gene transfected tumour cells

Elevated pretreatment serum levels of soluble vascular cell adhesion molecule 1 and lactate dehydrogenase as predictors of survival in cutaneous metastatic malignant melanoma

Expression of interleukin 6 (IL-6) correlates with oestrogen receptor in human breast carcinoma

Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair

An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells

Correction to: NFATc2 is an intrinsic regulator of melanoma dedifferentiation

Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade

Does the emergence and persistence of donor-derived leukaemia-reactive cytotoxic T lymphocytes protect patients given an allogeneic BMT from recurrence? Results of a preliminary study

Stimulation of urokinase-type plasminogen activator receptor expression by PMA requires JNK1-dependent and -independent signaling modules

Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder

Metastatic potential of human melanoma cells in nude mice - characterisation of phenotype, cytokine secretion and tumour-associated antigens

Pooled peptides from HER-2/neu-overexpressing primary ovarian tumours induce CTL with potent antitumour responses in vitro and in vivo

Emerging perovskite monolayers

Perifosine and sorafenib combination induces mitochondrial cell death and antitumor effects in NOD/SCID mice with Hodgkin lymphoma cell line xenografts

NFATc2 is an intrinsic regulator of melanoma dedifferentiation

Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma

(Epi)genotype–phenotype correlations in Beckwith–Wiedemann syndrome

BRAF alterations are associated with complex mutational profiles in malignant melanoma

EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells

BIM upregulation and ROS-dependent necroptosis mediate the antitumor effects of the HDACi Givinostat and Sorafenib in Hodgkin lymphoma cell line xenografts

Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib

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