The thickness of cortical layers varies among cortical areas. This study reports that the transcription factor AP2γ is specifically required for the generation of layer II/III neurons in the caudal primary visual cortex. Mice lacking AP2γ show impaired spatial resolution in visual cortex, whereas other parameters of visual cortex function remain close to normal.
- Luisa Pinto
- Daniela Drechsel
- Magdalena Götz