Nature Search

Proteinase inhibitor homologues as potassium channel blockers

Jean-Marc Lancelin
Marie-Françoise Foray
Dominique Marion
Research01 Apr 1994
Nature Structural Biology

Volume: 1, P: 246-250
Parallel clines of chromosomal inversion frequencies in seaweed flies are associated with thermal variation

Léa A. Nicolas
Emma L. Berdan
Claire Mérot
ResearchOpen Access05 Nov 2025
Heredity

P: 1-12
Ideology and polarization set the agenda on social media

Edoardo Loru
Alessandro Galeazzi
Walter Quattrociocchi
ResearchOpen Access14 Oct 2025
Scientific Reports

Volume: 15, P: 1-13
The crystal structure of human endothelin

Robert W. Janes
Diane H. Peapus
B.A. Wallace
Research01 May 1994
Nature Structural Biology

Volume: 1, P: 311-319
Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis

Interactions with the extracellular matrix (ECM) control tumor proliferation, invasion and metastasis. Here, authors provide spatial information on ECM organization and how it influences tumor cell invasive and metastasis properties through induction of cytoskeletal and transcriptional memory.

Oscar Maiques
Marta C. Sallan
Victoria Sanz-Moreno
ResearchOpen Access14 Feb 2025
Nature Communications

Volume: 16, P: 1-23
A worldwide survey of genome sequence variation provides insight into the evolutionary history of the honeybee Apis mellifera

Matthew Webster and colleagues report whole-genome sequencing of 140 honeybees from 14 worldwide populations. Their analyses provide insights into the evolutionary history and genetic basis of local adaptation in honeybees.

Andreas Wallberg
Fan Han
Matthew T Webster
Research24 Aug 2014
Nature Genetics

Volume: 46, P: 1081-1088
Evolution of fast-growing piscivorous herring in the young Baltic Sea

The Atlantic herring is one of the world’s most abundant vertebrates and a typical plankton feeder of major ecological importance. This study shows that a piscivorous (fish-eating) ecotype of herring has evolved after the colonization of the brackish Baltic Sea within the last 8,000 years.

Jake Goodall
Mats E. Pettersson
Leif Andersson
ResearchOpen Access23 Dec 2024
Nature Communications

Volume: 15, P: 1-13
Exercise type and muscle fiber specific induction of caveolin-1 expression for insulin sensitivity of skeletal muscle

Yoon Sin Oh
Hyo Jeong Kim
Sang Chul Park
ResearchOpen Access01 Jun 2007
Experimental & Molecular Medicine

Volume: 39, P: 395-401
The role of endothelial function and its assessment in rheumatoid arthritis

This Review discusses the role of endothelial dysfunction as a marker of the accelerated atherosclerosis associated with rheumatoid arthritis. The authors outline how the assessment of endothelial function could be useful in relation to the early identification and monitoring of cardiovascular risk in patients with the disease.

Faisel Khan
Bernat Galarraga
Jill J. F. Belch
Reviews30 Mar 2010
Nature Reviews Rheumatology

Volume: 6, P: 253-261
RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

The Ras GEF Ras-GRF2 is found to inhibit the activity of the Cdc42 Rho GTPase independently of its Ras-activating function. Binding of Ras-GRF2 to Cdc42 prevents its activation by Cdc42 GEFs suppressing Cdc42-mediated cell migration, invasion and transformation.

Fernando Calvo
Victoria Sanz-Moreno
Piero Crespo
Research19 Jun 2011
Nature Cell Biology

Volume: 13, P: 819-826
Cyclophosphamide exposure assessed with the biomarker phosphoramide mustard-hemoglobin in breast cancer patients: The TailorDose I study

S. A. M. Gernaat
H. von Stedingk
P. Rydberg
ResearchOpen Access01 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Polθ has been recently identified as a therapeutic target in cancer but specific inhibitors are currently unavailable. Here, the authors identify small molecule inhibitors of Polθ’s polymerase activity which elicit BRCA1/2 synthetic lethality, enhance the effect of PARP inhibitors and target PARP inhibitor resistance caused by 53BP1/Shieldin pathway defects.

Diana Zatreanu
Helen M. R. Robinson
Christopher J. Lord
ResearchOpen Access17 Jun 2021
Nature Communications

Volume: 12, P: 1-15
Fundamental questions in meiofauna research highlight how small but ubiquitous animals can improve our understanding of Nature

This paper identifies the top-50 priority questions for meiofaunal research, highlighting their critical roles in biogeochemical cycles and biodiversity. It calls for a balanced research agenda, international cooperation, and advances in technology to overcome current challenges and unlock meiofauna’s full potential.

Alejandro Martínez
Stefano Bonaglia
Diego Fontaneto
Comments & OpinionOpen Access17 Mar 2025
Communications Biology

Volume: 8, P: 1-17
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis

Endo180, a collagen binding receptor, is highly expressed in a subset of cancer-associated fibroblasts. The authors show, using knockout mice and 3D in vitro assays, that Endo180 depletion impairs tumour fibroblast contractility and viability resulting in reduced tumour growth and metastasis.

Ute Jungwirth
Antoinette van Weverwijk
Clare M. Isacke
ResearchOpen Access10 Jun 2021
Nature Communications

Volume: 12, P: 1-17
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Insulin resistance and type 2 diabetes mellitus are associated with mitochondrial dysfunction, and promoting healthy mitochondrial function could benefit patients. This Review discusses novel molecular targets for therapies that enhance mitochondrial function, with an emphasis on nonpharmacological regulation of factors such as nutrition, exercise, temperature and circadian rhythm.

Matthijs K. C. Hesselink
Vera Schrauwen-Hinderling
Patrick Schrauwen
Reviews22 Jul 2016
Nature Reviews Endocrinology

Volume: 12, P: 633-645
Recurrent bilateral renal calculi in a tetraplegic patient

S Vaidyanathan
B M Soni
K R Krishnan
Research07 Jun 1998
Spinal Cord

Volume: 36, P: 454-462
Noninvasive in vivo imaging of pancreatic islet cell biology

Stephan Speier
Daniel Nyqvist
Per-Olof Berggren
Research07 Mar 2008
Nature Medicine

Volume: 14, P: 574-578
Multi-omics for studying and understanding polar life

Endangered polar ecosystems play critical roles in the Earth’s climate system and comprise many different habitats with unique organisms. Here, the authors propose a community road map to use multi-omics data from polar organisms for conservation, ecosystem services and societal gain.

M. S. Clark
J. I. Hoffman
T. Mock
ReviewsOpen Access17 Nov 2023
Nature Communications

Volume: 14, P: 1-12
Obesity and increased contractile activity influence the protein content of UCP2 in human skeletal muscle

J-A Simoneau
DE Kelley
C Warden
Research13 Jul 1999
International Journal of Obesity

Volume: 23, P: S68-S71
The effects of exercise training on physical capacity, strength, body composition and functional performance among adults with spinal cord injury: a systematic review

A L Hicks
K A Martin Ginis
D L Wolfe
Research07 Jun 2011
Spinal Cord

Volume: 49, P: 1103-1127
Clinician and cancer patient views on patient participation in treatment decision-making: a quantitative and qualitative exploration

A H Pieterse
M C M Baas-Thijssen
A M Stiggelbout
ResearchOpen Access19 Aug 2008
British Journal of Cancer

Volume: 99, P: 875-882
Patient's needs and preferences in routine follow-up after treatment for breast cancer

G H de Bock
J Bonnema
A M Stiggelbout
ResearchOpen Access24 Feb 2004
British Journal of Cancer

Volume: 90, P: 1144-1150
Psychiatrically relevant signatures of domain-general decision-making and metacognition in the general population

Christopher S. Y. Benwell
Greta Mohr
Robin A. A. Ince
ResearchOpen Access30 Aug 2022
npj Mental Health Research

Volume: 1, P: 1-17
Whole genome SNP-associated signatures of local adaptation in honeybees of the Iberian Peninsula

Dora Henriques
Andreas Wallberg
M. Alice Pinto
ResearchOpen Access24 Jul 2018
Scientific Reports

Volume: 8, P: 1-14
Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson

D Menendez
A Inga
M A Resnick
Reviews02 Apr 2007
Oncogene

Volume: 26, P: 2191-2201
GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia

T Holmlund
M J Lindberg
A E Wallberg
Research11 Sept 2012
Leukemia

Volume: 27, P: 578-585
Retinoids in cancer therapy and chemoprevention: promise meets resistance

Sarah J Freemantle
Michael J Spinella
Ethan Dmitrovsky
Reviews23 Oct 2003
Oncogene

Volume: 22, P: 7305-7315
Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets

Nikola Dolezalova
Anja Gruszczyk
Kourosh Saeb-Parsy
ResearchOpen Access17 May 2021
Scientific Reports

Volume: 11, P: 1-18
Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

Stephan Speier
Daniel Nyqvist
Per-Olof Berggren
Protocols17 Jul 2008
Nature Protocols

Volume: 3, P: 1278-1286
Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells

Jenni Nikkilä
Rahul Kumar
Christopher J Lord
ResearchOpen Access23 May 2017
British Journal of Cancer

Volume: 117, P: 113-123
Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling

N Brimer
C Lyons
S B Vande Pol
Research16 Jan 2012
Oncogene

Volume: 31, P: 4639-4646
c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer

J L Regan
H Kendrick
M J Smalley
Research18 Jul 2011
Oncogene

Volume: 31, P: 869-883

Search

Proteinase inhibitor homologues as potassium channel blockers

Parallel clines of chromosomal inversion frequencies in seaweed flies are associated with thermal variation

Ideology and polarization set the agenda on social media

The crystal structure of human endothelin

Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis

A worldwide survey of genome sequence variation provides insight into the evolutionary history of the honeybee Apis mellifera

Evolution of fast-growing piscivorous herring in the young Baltic Sea

Exercise type and muscle fiber specific induction of caveolin-1 expression for insulin sensitivity of skeletal muscle

The role of endothelial function and its assessment in rheumatoid arthritis

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

Cyclophosphamide exposure assessed with the biomarker phosphoramide mustard-hemoglobin in breast cancer patients: The TailorDose I study

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Fundamental questions in meiofauna research highlight how small but ubiquitous animals can improve our understanding of Nature

Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis

Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Recurrent bilateral renal calculi in a tetraplegic patient

Noninvasive in vivo imaging of pancreatic islet cell biology

Multi-omics for studying and understanding polar life

Obesity and increased contractile activity influence the protein content of UCP2 in human skeletal muscle

The effects of exercise training on physical capacity, strength, body composition and functional performance among adults with spinal cord injury: a systematic review

Clinician and cancer patient views on patient participation in treatment decision-making: a quantitative and qualitative exploration

Patient's needs and preferences in routine follow-up after treatment for breast cancer

Psychiatrically relevant signatures of domain-general decision-making and metacognition in the general population

Whole genome SNP-associated signatures of local adaptation in honeybees of the Iberian Peninsula

Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson

GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia

Retinoids in cancer therapy and chemoprevention: promise meets resistance

Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells

Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling

c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer

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