Partial nephrectomy is associated with ischemia–reperfusion injury caused by vascular clamping. However, ischemia is not a vital part of the procedure, and nonclamping surgery can be carried out. In this Perspectives, the authors review the evidence regarding clamping and nonclamping partial nephrectomy, and discuss their own surgical experiences with these techniques.
- Matthew F. Wszolek
- Patrick A. Kenney
- John A. Libertino