In this Review, Kocher, Krause and Spyrou explore how ancient pathogen genomics is providing new perspectives on the history and evolution of infectious agents. They show how ancient DNA has revealed the aetiology and unfolding of historic outbreaks, pathogen evolutionary timescales, patterns of dissemination and functional evolution, and discuss existing limitations and perspectives of the field.
- Arthur Kocher
- Johannes Krause
- Maria A. Spyrou