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Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial

The COMPASS trial is a prospective observational study seeking to establish biomarkers in advanced pancreatic cancer through in-depth profiling prior to commencing chemotherapy. Here, the authors report the final data for the complete cohort of 268 patients enrolled in the COMPASS trial.

Jennifer J. Knox
Gun Ho Jang
Grainne M. O’Kane
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Mechanism of tandem duplication formation in BRCA1-mutant cells

BRCA1, but not BRCA2, suppresses the formation of tandem duplications at stalled replication forks in primary mammalian cells.

Nicholas A. Willis
Richard L. Frock
Ralph Scully
Research22 Nov 2017
Nature

Volume: 551, P: 590-595
The potential role of MR based radiomic biomarkers in the characterization of focal testicular lesions

Giacomo Feliciani
Lorenzo Mellini
Gian Carlo Parenti
ResearchOpen Access10 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis

Edoardo Rosato
Rosario Cianci
Felice Salsano
Research04 Sept 2009
Acta Pharmacologica Sinica

Volume: 30, P: 1283-1288
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

A pan-cancer analysis finds that extrachromosomal DNA is pervasive and associated with oncogene amplification and poor patient outcomes.

Hoon Kim
Nam-Phuong Nguyen
Roel G. W. Verhaak
Research17 Aug 2020
Nature Genetics

Volume: 52, P: 891-897
Reduced expression of BAX is associated with poor prognosis in patients with epithelial ovarian cancer: a multifactorial analysis of TP53, p21, BAX and BCL-2

M Schuyer
M E L van der Burg
E M J J Berns
ResearchOpen Access30 Oct 2001
British Journal of Cancer

Volume: 85, P: 1359-1367
Expression of apoptosis-related markers and clinical outcome in patients with advanced colorectal cancer

A Paradiso
G Simone
A Costa
ResearchOpen Access27 Feb 2001
British Journal of Cancer

Volume: 84, P: 651-658
Zinc therapy in an infant with Acrodermatitis Enteropathica: clinical and imnunological result: 86

L Businco
A M Menghi
E Galli
Research01 Feb 1980
Pediatric Research

Volume: 14, P: 179
Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome

A Schramm
B Schowe
J H Schulte
ResearchOpen Access09 Oct 2012
British Journal of Cancer

Volume: 107, P: 1409-1417
Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients

A Ruzzo
F Graziano
M Magnani
ResearchOpen Access24 Aug 2017
British Journal of Cancer

Volume: 117, P: 1269-1277

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Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial

Mechanism of tandem duplication formation in BRCA1-mutant cells

The potential role of MR based radiomic biomarkers in the characterization of focal testicular lesions

N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

Reduced expression of BAX is associated with poor prognosis in patients with epithelial ovarian cancer: a multifactorial analysis of TP53, p21, BAX and BCL-2

Expression of apoptosis-related markers and clinical outcome in patients with advanced colorectal cancer

Zinc therapy in an infant with Acrodermatitis Enteropathica: clinical and imnunological result: 86

Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome

Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients

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