Nature Search

Human intestinal pro-inflammatory CD11c^highCCR2⁺CX3CR1⁺ macrophages, but not their tolerogenic CD11c⁻CCR2⁻CX3CR1⁻ counterparts, are expanded in inflammatory bowel disease

D. Bernardo
A. C. Marin
J. P. Gisbert
Research09 May 2018
Mucosal Immunology

Volume: 11, P: 1114-1126
Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease

Celiac disease is linked to responsiveness to dietary gluten, which manifests itself as immune cell activation and the immunopathology including destruction of the epithelium of the small intestine. Here the authors apply single cell transcriptomics to characterise the immune cell compartment of the human small intestine during active Celiac disease.

Nader Atlasy
Anna Bujko
Hendrik G. Stunnenberg
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-14
The current landscape of locally advanced rectal cancer

Current treatments for patients with locally advanced rectal cancer (LARC) consist of neoadjuvant chemoradiotherapy, followed by total mesorectal excision and adjuvant chemotherapy. Aklilu and Eng review the pivotal trials that have led to this treatment paradigm and discuss novel therapies that are being developed for patients with LARC.

Mebea Aklilu
Cathy Eng
Reviews09 Aug 2011
Nature Reviews Clinical Oncology

Volume: 8, P: 649-659
The impact of large-scale agricultural investments on welfare of local communities: a meta-analysis

Lingerh Sewnet Akalu
Huashu Wang
Fentahun Baylie
ReviewsOpen Access06 Aug 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-15
Organ preservation with local excision or active surveillance following chemoradiotherapy for rectal cancer

B Creavin
E Ryan
D C Winter
ResearchOpen Access20 Dec 2016
British Journal of Cancer

Volume: 116, P: 169-174
International consensus recommendations on key outcome measures for organ preservation after (chemo)radiotherapy in patients with rectal cancer

Patients with early-stage rectal cancer might potentially benefit from treatment with an organ-sparing approach, which preserves quality of life owing to avoidance of the need for permanent colostomy. Trials conducted to investigate this have so far been hampered by considerable inter-trial heterogeneity in several key features. In this Consensus Statement, the authors provide guidance on the optimal end points, response assessment time points, follow-up procedures and quality of life measures in an attempt to improve the comparability of clinical research in this area.

Emmanouil Fokas
Ane Appelt
Claus Rödel
Reviews04 Aug 2021
Nature Reviews Clinical Oncology

Volume: 18, P: 805-816
Combined analysis of VEGF and EGFR predicts complete tumour response in rectal cancer treated with preoperative radiotherapy

I Zlobec
T Vuong
J R Jass
ResearchOpen Access08 Jan 2008
British Journal of Cancer

Volume: 98, P: 450-456
DMRTA2 supports glioma stem-cell mediated neovascularization in glioblastoma

Marta Maleszewska
Kamil Wojnicki
Bozena Kaminska
ResearchOpen Access20 Mar 2024
Cell Death & Disease

Volume: 15, P: 1-10
Practice-changing radiation therapy trials for the treatment of cancer: where are we 150 years after the birth of Marie Curie?

Mareike K. Thompson
Philip Poortmans
Charlotte E. Coles
ReviewsOpen Access31 Jul 2018
British Journal of Cancer

Volume: 119, P: 389-407
Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine

L. Richter
O. J. B. Landsverk
F. L. Jahnsen
Research23 Jul 2018
Mucosal Immunology

Volume: 11, P: 1512-1523
Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1

A Abdelbaset-Ismail
S Borkowska-Rzeszotek
M Z Ratajczak
ResearchOpen Access25 Jul 2016
Leukemia

Volume: 31, P: 446-458

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