Drug combination therapy is often required to overcome the limited benefits of monotherapy in cancer treatment. Here the authors present SynergyLMM, which harmonizes analyses of drug combination experiments in animal studies, helping researchers statistically test synergy and antagonism, design well-powered experiments, and enhancing eventual translation to more effective combination therapies.
- Rafael Romero-Becerra
- Zhi Zhao
- Tero Aittokallio
