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Showing 1–9 of 9 results
Advanced filters: Author: A. Vania Apkarian Clear advanced filters

  • Technology for peering into the brain is revealing a pattern of pain, and differences between the acute and chronic forms.

    • Simon Makin
    Comments & Opinion
    Nature
    Volume: 535, P: S8-S9

  • Brain-scanning techniques promise to give an objective measure of whether someone is in pain, but researchers question whether they are reliable enough for the courtroom.

    • Sara Reardon
    News
    Nature
    Volume: 518, P: 474-476

  • People vary in the extent to which they feel better after taking an inert, placebo, treatment, but the basis for individual placebo response is unclear. Here, the authors show how brain structural and functional variables, as well as personality traits, predict placebo response in those with chronic back pain.

    • Etienne Vachon-Presseau
    • Sara E. Berger
    • A. Vania Apkarian
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15

  • In a longitudinal brain imaging study, patients with subacute back pain were followed over the course of 1 year. Initially greater functional connectivity of nucleus accumbens with prefrontal cortex predicted pain persistence, implying that corticostriatal circuitry is causally involved in the transition from acute to chronic pain.

    • Marwan N Baliki
    • Bogdan Petre
    • A Vania Apkarian
    Research
    Nature Neuroscience
    Volume: 15, P: 1117-1119

  • Neuropathic pain poses a major healthcare burden. The authors show that a specific set of neurons in the nucleus accumbens, a region long associated with affect, were changed in a mouse model of neuropathic pain. A pharmacotherapy that is well tolerated in man reversed these adaptations and alleviated pain.

    • Wenjie Ren
    • Maria Virginia Centeno
    • D James Surmeier
    Research
    Nature Neuroscience
    Volume: 19, P: 220-222

  • This Review discusses how pain in osteoarthritis might involve adaptations of brain circuits, and suggests that osteoarthritis pain management should consider targeting central mechanisms of pain in addition to nociceptive neuron activity.

    • Joana Barroso
    • Paulo Branco
    • A. Vania Apkarian
    Reviews
    Nature Reviews Rheumatology
    Volume: 21, P: 261-274