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  • A small-molecule inhibitor of TMPRSS2 is effective against SARS-CoV-2 variants of concern in human lung cells and in donor-derived colonoids, and also shows prophylactic and therapeutic benefits in a mouse model of COVID-19.

    • Tirosh Shapira
    • I. Abrrey Monreal
    • François Jean
    ResearchOpen Access
    Nature
    Volume: 605, P: 340-348