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Showing 1–2 of 2 results
Advanced filters: Author: Aaron Cravens Clear advanced filters

  • Existing in vivo mutagenesis tools are limited by low mutation diversity and mutation rates. Here the authors present TRIDENT for targeted, continual and inducible diversification of genes of interest using deaminases fused to T7 RNA polymerase.

    • Aaron Cravens
    • Osman K. Jamil
    • Christina D. Smolke
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Engineering microbial cell factories for the production of useful plant natural products (PNPs) is a resource-conserving and environmentally-friendly synthesis route. Here, the authors review recent developments that enable engineering of hosts, pathways, and enzymes to make PNPs and PNP derivatives.

    • Aaron Cravens
    • James Payne
    • Christina D. Smolke
    ReviewsOpen Access
    Nature Communications
    Volume: 10, P: 1-12