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Showing 1–3 of 3 results
Advanced filters: Author: Aaron W. Lifland Clear advanced filters

  • Upon binding multiple fluorophores and being complexed into tetramers, these RNA imaging probes show high sensitivity and can detect single endogenous RNA molecules at low probe concentration.

    • Philip J Santangelo
    • Aaron W Lifland
    • James E Crowe Jr
    Research
    Nature Methods
    Volume: 6, P: 347-349

  • Assembly of filamentous RSV particles is incompletely understood due to a lack of techniques suitable for live-cell imaging. Here Vanover et al. use labeled soybean agglutinin to selectively label RSV G protein and show how filamentous RSV assembly, initiated in the cytoplasm, uses G protein recycled from the plasma membrane.

    • Daryll Vanover
    • Daisy V. Smith
    • Philip J. Santangelo
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15

  • Engineered neutralizing antibodies are potential therapeutics for numerous viruses, such as respiratory syncytial virus (RSV). Here, the authors develop an mRNA-based approach to express membrane-anchored neutralizing antibodies in the lung and demonstrate that it inhibits RSV infections in mice.

    • Pooja Munnilal Tiwari
    • Daryll Vanover
    • Philip J. Santangelo
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15