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Showing 1–15 of 15 results
Advanced filters: Author: Aaron van Donkelaar Clear advanced filters

  • Global fine particulate matter air pollution recently pivots from increase to decrease as inferred from satellite observations, driven by unprecedented exposure reduction in China and slowed exposure growth in South Asia, the Middle East and Africa.

    • Chi Li
    • Aaron van Donkelaar
    • Randall V. Martin
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12

  • Globally, urban areas experienced increases in ozone concentrations from 2005 to 2019, whereas fine particulate matter, nitrogen dioxide, and fossil-fuel carbon dioxide emissions showed non-significant variations, according to analysis of large geospatial air pollution datasets.

    • Soo-Yeon Kim
    • Gaige Hunter Kerr
    • Susan C. Anenberg
    ResearchOpen Access
    Communications Earth & Environment
    Volume: 6, P: 1-14

  • Carbon dioxide emissions and air pollution are often assessed on a national or regional level, but little is known about the role of trade structures. Here, a combination of models shows that trade restrictions can lead to massive reduction of gross domestic product in most countries, but also to a reduction of emissions and pollution.

    • Jintai Lin
    • Mingxi Du
    • Klaus Hubacek
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • Genome-wide analysis identifies variants associated with the volume of seven different subcortical brain regions defined by magnetic resonance imaging. Implicated genes are involved in neurodevelopmental and synaptic signaling pathways.

    • Claudia L. Satizabal
    • Hieab H. H. Adams
    • M. Arfan Ikram
    Research
    Nature Genetics
    Volume: 51, P: 1624-1636

  • The hippocampus in mammalian brain varies in size across individuals. Here, Hibar and colleagues perform a genome-wide association meta-analysis to find six genetic loci with significant association to hippocampus volume.

    • Derrek P. Hibar
    • Hieab H. H. Adams
    • M. Arfan Ikram
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • In a GWAS study of 32,438 adults, the authors discovered five novel loci for intracranial volume and confirmed two known signals. Variants for intracranial volume were also related to childhood and adult cognitive function and to Parkinson's disease, and enriched near genes involved in growth pathways, including PI3K-AKT signaling.

    • Hieab H H Adams
    • Derrek P Hibar
    • Paul M Thompson
    Research
    Nature Neuroscience
    Volume: 19, P: 1569-1582

  • The authors defined a roadmap for investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders. Their proof-of-concept study using the largest available common variant data sets for schizophrenia and volumes of several (mainly subcortical) brain structures did not find evidence of genetic overlap.

    • Barbara Franke
    • Jason L Stein
    • Patrick F Sullivan
    Research
    Nature Neuroscience
    Volume: 19, P: 420-431

  • Cortex morphology varies with age, cognitive function, and in neurological and psychiatric diseases. Here the authors report 160 genome-wide significant associations with thickness, surface area and volume of the total cortex and 34 cortical regions from a GWAS meta-analysis in 22,824 adults.

    • Edith Hofer
    • Gennady V. Roshchupkin
    • Sudha Seshadri
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • Ambient fine particulate matter (PM2.5) is one of the most important environmental health risk factors in many regions. Here, the authors present an assessment of PM2.5 emission sources and the related health impacts across global to sub-national scales and find that over 1 million deaths were avoidable in 2017 by eliminating PM2.5 mass associated with fossil fuel combustion emissions.

    • Erin E. McDuffie
    • Randall V. Martin
    • Michael Brauer
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Genome-wide association studies are used to identify common genetic variants that affect the structure of selected subcortical regions of the human brain; their identification provides insight into the causes of variability in brain development and may help to determine mechanisms of neuropsychiatric dysfunction.

    • Derrek P. Hibar
    • Jason L. Stein
    • Sarah E. Medland
    Research
    Nature
    Volume: 520, P: 224-229

  • Genome-wide analysis of self-reported dyslexia identifies 42 associated loci, including 27 not previously associated with cognitive traits. Dyslexia shows genetic correlation with ambidexterity but not neuroanatomical measures of language-related circuitry.

    • Catherine Doust
    • Pierre Fontanillas
    • Michelle Luciano
    ResearchOpen Access
    Nature Genetics
    Volume: 54, P: 1621-1629

  • Monetary damages from exposure to particulate matter and carbon dioxide emissions peak later on countries’ development path than total emissions and concentration and may, therefore, make better sustainability metrics according to an analysis of air quality and economic data of 165 countries.

    • Aniruddh Mohan
    • Nicholas Z. Muller
    • Aaron van Donkelaar
    ResearchOpen Access
    Communications Earth & Environment
    Volume: 5, P: 1-10